Shinya Yamada M.D Ph.D

Juntendo University, Neurosurgery, Tokyo, Japan
Consulting Neurosurgeon, Kugayama Hospital, Tokyo, Japan

Lecture Title: Cerebrospinal Fluids Dynamics in Normal and Hydrocephalus Brain

Dr. Shinya Yamada is a consulting neurosurgeon at Kugayama Hospital　and is affiliated with the Department of Neurosurgery at Juntendo University in Tokyo, Japan, whose research centers around cerebrospinal fluid and interstitial fluid. He was trained in brain interstitial fluid clearance and its drainage to the lymphatics as a research fellow in the Brain Physiology Lab at Brown University in Rhode Island, USA. Since then, Shinya Yamada has focused especially on the physiology of cerebrospinal fluid (CSF) and interstitial fluid (ISF) research. He developed quantitative amyloid-beta clearance from the brain micro-injection model at the University of Southern California, the first discovery of quantitative AB clearance from the brain. He also invented an MRI sequence called the Time-spatial Labeling Inversion Pulse (Time-Slip) method that can noninvasively observe the dynamics of CSF. This MRI technique is very helpful for understanding CSF dynamics in individual cases and provides important information for treatment strategies. He has discovered that CSF physiology is quite different from previously thought.